Avascular Necrosis Treatment Options
Avascular necrosis (AVN)—also known as osteonecrosis—is a condition in which the blood supply to a bone is disrupted, leading to the death of bone tissue. Without adequate circulation, the affected bone can weaken, collapse, and eventually lead to joint dysfunction. AVN most commonly affects the hip joint (femoral head), but it can also occur in the shoulder, knee, or other joints.
AVN can develop due to trauma (like a hip fracture or dislocation), certain medical conditions (e.g., lupus or sickle cell disease), chronic steroid use, alcohol abuse, or sometimes without a clear cause (idiopathic). Treatment depends on the stage of the disease, the joint involved, and the patient’s activity level and overall health.
At Lall Orthopedics+, we offer a full range of evidence-based treatments—both non-surgical and surgical—to manage AVN and preserve joint function for as long as possible.
Activity Modification and Weight-Bearing Restrictions
Reducing stress on the affected joint is critical. Patients may be advised to limit high-impact activities and use crutches or a cane to offload weight, particularly if the hip is involved. This can help prevent further bone damage during the early stages of AVN.
Medications
While there are no medications that can reverse AVN, certain drugs may be used to manage symptoms or slow progression:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen can help control pain and inflammation.
- Bisphosphonates, which are typically used to treat osteoporosis, have been studied for their potential to prevent bone collapse in AVN, although their effectiveness is still debated.
- Anticoagulants may be used if AVN is associated with clotting disorders or to improve blood flow in certain cases.
- Physical Therapy
A supervised physical therapy program can maintain joint mobility, strengthen surrounding muscles, and help reduce pain. However, therapy must be carefully managed to avoid stressing the compromised bone
Electrical Stimulation and Bone Growth Stimulator
Some patients may benefit from pulsed electromagnetic field (PEMF) therapy or electrical stimulation, which are designed to encourage bone healing and regeneration. These are typically used in early-stage AVN and are considered adjunctive therapies.
When AVN progresses and the bone begins to collapse, surgical treatment becomes the most effective option. The choice of surgery depends on the stage of the disease, the patient’s age, and the specific joint affected.
Core Decompression
Core decompression is often used in early to mid-stage AVN before significant bone collapse has occurred. In this procedure, a surgeon drills one or more channels into the necrotic area of the bone to reduce pressure, improve blood flow, and stimulate healing. In some cases, bone grafts or biologic materials (e.g., stem cells or bone marrow aspirate) are added to enhance bone regeneration. Many patients experience pain relief and slowed disease progression with this minimally invasive option.
Bone Grafting
When a larger area of bone is affected or if the structural integrity of the bone is compromised, bone grafting may be used to replace damaged tissue and support the joint. This can be done in conjunction with core decompression or as part of more extensive reconstruction procedures. Grafts may be autografts (from the patient’s own body) or allografts (donor tissue).
Osteotomy
An osteotomy involves cutting and repositioning the bone to shift weight away from the area affected by AVN. This joint-preserving procedure is usually reserved for younger patients and is more commonly performed in the knee than in the hip. The goal is to redistribute mechanical load and delay the need for joint replacement.
Total Joint Replacement (Arthroplasty)
If AVN has advanced to the point of joint collapse and arthritis, total joint replacement becomes the most reliable solution. In the case of hip AVN, a total hip replacement can relieve pain and restore mobility with long-term success. Advances in implant technology and surgical techniques have made this procedure highly effective, even for younger and more active patients.
At a Glance
Ajay C. Lall, MD, MS, FAAOS
- Board Certified – Orthopedic Surgery
- Triple Fellowship Trained
- Performs over 750 Surgeries Per Year
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